Profile Hidden Markov Models Are Not Identifiable
نویسندگان
چکیده
منابع مشابه
Profile hidden Markov models
The recent literature on profile hidden Markov model (profile HMM) methods and software is reviewed. Profile HMMs turn a multiple sequence alignment into a position-specific scoring system suitable for searching databases for remotely homologous sequences. Profile HMM analyses complement standard pairwise comparison methods for large-scale sequence analysis. Several software implementations and...
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ژورنال
عنوان ژورنال: IEEE/ACM Transactions on Computational Biology and Bioinformatics
سال: 2021
ISSN: 1545-5963,1557-9964,2374-0043
DOI: 10.1109/tcbb.2019.2933821